Nitric Oxide (NO) In Acne Prone Skin

Nitric oxide (NO) has several potential functions in acne care.

Acne is a common skin condition that occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and whiteheads.

Several areas in which nitric oxide may play a key role

Reducing Inflammation

One of the hallmarks of acne is inflammation, which can cause redness, swelling, and pain. Nitric oxide has anti-inflammatory properties, which may help to reduce the severity of acne symptoms. By inhibiting the production of pro-inflammatory cytokines and chemokines, NO can help to calm the immune response and prevent further damage to the skin.

Regulating Sebum Production

Excessive sebum production is a major contributor to acne, as it can clog pores and create an environment for bacteria to thrive. Nitric oxide has been shown to regulate sebum production by inhibiting the activity of sebaceous glands. By reducing sebum production, NO can help to prevent the formation of new acne lesions.

Killing Acne-Causing Bacteria

Propionibacterium acnes (P. acnes) is a type of bacteria that is commonly associated with acne. Nitric oxide has antimicrobial properties, which may help to kill P. acnes and other bacteria that contribute to acne. By eliminating these bacteria, NO can help to reduce the number of acne lesions and prevent new ones from forming.

Promoting Wound Healing

Acne lesions can cause damage to the skin, leading to scarring and hyperpigmentation. Nitric oxide can help to promote wound healing by increasing blood flow and stimulating collagen production. By repairing damaged tissue, NO can help to prevent long-term damage from acne lesions.

Side by side views of a before and after photo, on the left, a cheek with acne, on the right, clear skin.

A Valuable Addition to Acne Care

Overall, nitric oxide has the potential to be a valuable addition to acne care, particularly for those with inflammatory acne.